JENNER, Edward (1749-1823). An Inquiry into the Causes and Effects of the Variolæ Vaccinæ, London, 1801, 4to, 4 engraved hand-coloured plates, contemporary calf (rebacked). Third edition. With a facsimile of the 1798 edition and a related document. (3)

JENNER, Edward (1749-1823).  An Inquiry into the Causes and Effects of the Variolæ Vaccinæ, a Disease Discovered in Some of the Western Counties of England, Particularly Gloucestershire, and Known by the name of The Cow Pox ... The Third Edition. London: Printed for the Author, by D. N. Shury, 1801. 4to (268 x 215mm). 4 engraved hand-coloured plates (repair to lower fore-corner of title without loss, many text leaves browned and stained although the plates generally cleaner). Contemporary calf (rebacked, corners repaired, rubbed and scuffed, inner hinges reinforced). Provenance: From the Collection of Professor Jonathan Brostoff, D.M., D.Sc., FRCP, FRCPath (1934-2020); [?]Geo. [?]Borton (old signature at head of title); Peterborough Public Dispensary (stamp on title). "Jenner's work is the basis of the modern science of immunology. When Pasteur successfully inoculated sheep against anthrax he called such preventive inoculations 'vaccines' [from the Latin for cow] in honour of Jenner ... Jenner had started one of the greatest practical advances in preventive medicine ..." (PMM). Dibner Heralds of Science 127; Garrison & Morton 5423: "Jenner established the fact that a 'vaccination' or inoculation with vaccinia (cowpox) lymph matter protects against smallpox ... [The Inquiry], describing 23 successful vaccinations, announced to the world one of the greatest triumphs in the history of medicine"; Grolier Medicine 53; Heirs of Hippocrates 1086; William Lefanu Edward Jenner 8; Norman 1162; PMM 250; Wellcome III, p.351 (references citing the first edition of 1798). With a modern facsimile of the 1798 edition in boards and a framed manuscript document recording vaccinations for measles administered to members of the family of William Gustard, c.1830. (3)