CASAL, Gaspar (1680-1759). Historia Natural, y Medica de el Principado de Asturias. Obra. Posthuma. Madrid, 1762, 4to, engraved frontispiece (some staining), contemporary vellum. Provenance: From the Collection of John Yudkin (bookplate). FIRST EDITION.

CASAL, Gaspar (1680-1759).  Historia Natural, y Medica de el Principado de Asturias. Obra Posthuma ... La Saca a Luz el Doct. Juan Joseph Garcia. Madrid: "En la Oficina de Manuel Martin, Calle de la Cruz," 1762. 4to (204 x 145mm). Engraved frontispiece, woodcut initials and ornaments (waterstain to frontispiece, some other staining). Contemporary vellum, remnants of printed label on spine. Provenance: From the Collection of Professor John Yudkin (modern bookplate; please see the biographical note at the end of lot 308). FIRST EDITION. The author was a Spanish physician best remembered for first describing the eponymous "Casal Collar" associated with the disease of pellagra or "Asturian leprosy", and his account in the present volume (on p.327, under the heading: "De affectione, quæ Vulgò in hac Regione mal de Rosa [a Spanish term for Pellagra] nuncupator") is recognised as the first modern pathological description not only of the disease, but of any syndrome. Garrison & Morton 1771: "Includes the first full description of pellagra. Casal wrote the book in 1735, but it was not published until 1762; a reprint was published in Oviedo in 1900"; Palau 46731.